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KMID : 0387720140250030274
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Korean Journal of Blood Transfusion
2014 Volume.25 No. 3 p.274 ~ p.282
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Factors Affecting the Freshness of Transfused Packed Red Blood Cells
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육희정:Youk Hee-Jeong
조치현:Cho Chi-Hyun/최지선:Choi Ji-Seon/남명현:Nam Myung-Hyun/임채승:Lim Chae-Seung/이창규:Lee Chang-Kyu/조윤정:Jo Yun-Jung
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Abstract
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Background: The relationship between the storage age of packed red blood cells (pRBCs) and clinical outcomes is controversial. However, no systematic study regarding how fresh pRBCs were transfused to patients have been available so far. Therefore, we newly defined concepts for supply age (period from blood collection to supply to hospital), storage age (period from supply to transfusion to patient), and transfusion age (supply age plus storage age) and investigated them. The factors affecting each age were also analyzed.
Methods: A retrospective analysis for three ages of pRBCs was performed for patients who were transfused ≥1 pRBCs unit at three university hospitals between January 2009 and December 2013. Inventory age (period from blood collection to inventory check point at each blood bank) was prospectively checked on a daily basis for 30 days. Four blood centers and blood groups of transfused pRBCs were included.
Results: The mean supply, storage, and transfusion ages of pRBCs were 6.2, 6.0, and 12.0 days, respectively. 58%, 61%, and 66% of total transfused pRBCs were in a fresh category of supply, storage, and transfusion ages correspondingly. Storage and transfusion ages were affected by ABO blood group, hospitals, and years in listing orders. Inventory age was mainly affected by ABO blood group and hospitals.
Conclusion: The freshness of transfused pRBCs was affected by hospitals and blood centers. Therefore, using the supply, storage, transfusion, and inventory ages as new norms can be useful to establishment of inventory and supply policies of hospitals and blood centers.
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KEYWORD
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pRBCs, Supply age, Storage age, Transfusion age, Inventory age, Policy
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